Journal article
The Psychopathology and Neuroanatomical Markers of Depression in Early Psychosis
R Upthegrove, P Lalousis, P Mallikarjun, K Chisholm, SL Griffiths, M Iqbal, M Pelton, R Reniers, A Stainton, M Rosen, A Ruef, DB Dwyer, M Surman, T Haidl, N Penzel, L Kambeitz-Llankovic, A Bertolino, P Brambilla, S Borgwardt, J Kambeitz Show all
Schizophrenia Bulletin | OXFORD UNIV PRESS | Published : 2021
Abstract
Depression frequently occurs in first-episode psychosis (FEP) and predicts longer-term negative outcomes. It is possible that this depression is seen primarily in a distinct subgroup, which if identified could allow targeted treatments. We hypothesize that patients with recent-onset psychosis (ROP) and comorbid depression would be identifiable by symptoms and neuroanatomical features similar to those seen in recent-onset depression (ROD). Data were extracted from the multisite PRONIA study: 154 ROP patients (FEP within 3 months of treatment onset), of whom 83 were depressed (ROP+D) and 71 who were not depressed (ROP-D), 146 ROD patients, and 265 healthy controls (HC). Analyses included a (1)..
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Grants
Awarded by European Commission
Funding Acknowledgements
The PRONIA study is a Collaboration Project funded under the 7th Framework Programme under grant agreement no 602152.